Pub. Date : 2016 Oct 17
PMID : 27484786
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization. | Methyl Methanesulfonate | BRCA1 DNA repair associated | Homo sapiens |
2 | We propose a model where BRCA1 cancer variants interact with the DNA double strand break repair pathways producing DNA recombination intermediates, that maybe less repairable and decrease MMS-induced recombination and survival. | Methyl Methanesulfonate | BRCA1 DNA repair associated | Homo sapiens |