Title : Binding Mechanism of Inhibitors to CDK5/p25 Complex: Free Energy Calculation and Ranking Aggregation Analysis.

Pub. Date : 2013 Mar

PMID : 27481520






1 Functional Relationships(s)
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1 Besides the hydrogen bond formation, the van der Waals interactions between residues Ile10, Val18, and Leu133 of CDK5 and inhibitors were discovered to constitute another substantial component of their binding mode. Hydrogen cyclin dependent kinase 5 Homo sapiens