Title : Histone deacetylase inhibitors stimulate the susceptibility of A549 cells to a plasma-activated medium treatment.

Pub. Date : 2016 Sep 15

PMID : 27470189






2 Functional Relationships(s)
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1 Cell death with DNA breaks in the nucleus was greater using combined regimens of PAM and HDAC inhibitors such as trichostatin A (TSA) and valproic acid (VPA) than a single PAM treatment and was accompanied by the activation of poly (ADP-ribose) polymerase-1 (PARP-1), depletion of ATP, and elevations in intracellular calcium levels. Valproic Acid histone deacetylase 9 Homo sapiens
2 Cell death with DNA breaks in the nucleus was greater using combined regimens of PAM and HDAC inhibitors such as trichostatin A (TSA) and valproic acid (VPA) than a single PAM treatment and was accompanied by the activation of poly (ADP-ribose) polymerase-1 (PARP-1), depletion of ATP, and elevations in intracellular calcium levels. Valproic Acid histone deacetylase 9 Homo sapiens