Pub. Date : 2016 Sep 15
PMID : 27466197
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, pridopidine treatment upregulated the glucocorticoid receptor (GR) response, D1R-associated genes and the AKT/PI3K pathway (P = 1E-10, P = 0.001, P = 0.004, respectively). | pridopidine | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Pridopidine upregulates expression of BDNF, D1R, GR and AKT/PI3K pathways, known to promote neuronal plasticity and survival, as well as reported to demonstrate therapeutic benefit in HD animal models. | pridopidine | thymoma viral proto-oncogene 1 | Mus musculus |