Title : Manic symptom severity correlates with COMT activity in the striatum: A post-mortem study.

Pub. Date : 2017 Apr

PMID : 27458023






2 Functional Relationships(s)
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1 OBJECTIVES: The enzyme catechol-O-methyltransferase (COMT), which catalyses the degradation of dopamine and norepinephrine, is posited to participate in the pathophysiology of bipolar disorder (BD) and schizophrenia. Norepinephrine catechol-O-methyltransferase Homo sapiens
2 OBJECTIVES: The enzyme catechol-O-methyltransferase (COMT), which catalyses the degradation of dopamine and norepinephrine, is posited to participate in the pathophysiology of bipolar disorder (BD) and schizophrenia. Norepinephrine catechol-O-methyltransferase Homo sapiens