Title : The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype.

Pub. Date : 2016 Oct

PMID : 27432892






1 Functional Relationships(s)
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1 The renal outer medullary potassium (ROMK) channel, located at the apical surface of epithelial cells in the thick ascending loop of Henle and cortical collecting duct, contributes to salt reabsorption and potassium secretion, and represents a target for the development of new mechanism of action diuretics. Potassium potassium inwardly rectifying channel subfamily J member 1 Homo sapiens