Pub. Date : 2016 Sep
PMID : 27414741
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | ROS-mediated apoptosis of HAPI microglia through p53 signaling following PFOS exposure. | ros | tumor protein p53 | Homo sapiens |
2 | Interestingly, NAC, a ROS inhibitor, inhibited p53 expression, and decreased the apoptosis of HAPI microglia. | ros | tumor protein p53 | Homo sapiens |
3 | Taken together, these findings suggest that upregulated production of ROS plays a vital role in PFOS-mediated apoptosis in HAPI microglia via the modulation of p53 signaling. | ros | tumor protein p53 | Homo sapiens |