Title : ROS-mediated apoptosis of HAPI microglia through p53 signaling following PFOS exposure.

Pub. Date : 2016 Sep

PMID : 27414741






3 Functional Relationships(s)
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1 ROS-mediated apoptosis of HAPI microglia through p53 signaling following PFOS exposure. ros tumor protein p53 Homo sapiens
2 Interestingly, NAC, a ROS inhibitor, inhibited p53 expression, and decreased the apoptosis of HAPI microglia. ros tumor protein p53 Homo sapiens
3 Taken together, these findings suggest that upregulated production of ROS plays a vital role in PFOS-mediated apoptosis in HAPI microglia via the modulation of p53 signaling. ros tumor protein p53 Homo sapiens