Title : Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression.

Pub. Date : 2016 Jul 11

PMID : 27405597






1 Functional Relationships(s)
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1 Here we show that methane-rich saline (MS) ip treatment (16 ml/kg) alleviated endotoxin shock, bacteria-induced sepsis and dextran-sulfate-sodium-induced colitis in mice via decreased production of TNF-alpha and IL-6. Methane tumor necrosis factor Mus musculus