Title : The eicosanoids leukotriene D4 and prostaglandin E2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model.

Pub. Date : 2016 Jul 7

PMID : 27388564






2 Functional Relationships(s)
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1 In addition, LTD4 and PGE2 treatment significantly elevated the plasma levels of cysteinyl leukotrienes and PGE2, as well as levels of IL-1beta, IL-2, IL-6, TNF-alpha and CXCL1/KC/GRO. Dinoprostone interleukin 1 beta Mus musculus
2 In addition, increased mRNA expression of IL-1beta, IL-6 and IL-10 were detected in tumors from mice that had been treated with LTD4 or PGE2. Dinoprostone interleukin 1 beta Mus musculus