Title : Two Alkaloids from Bulbs of Lycoris sanguinea MAXIM. Suppress PEPCK Expression by Inhibiting the Phosphorylation of CREB.

Pub. Date : 2016 Oct

PMID : 27388056






1 Functional Relationships(s)
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1 In forskolin-stimulated human hepatoma cells, these alkaloids suppressed the expression of a reporter gene under the control of cAMP response element and also prevented increases in the endogenous levels of phosphorylated CREB and PEPCK mRNA expression. Colforsin cAMP responsive element binding protein 1 Homo sapiens