Title : Mutant p53 and mTOR/PKM2 regulation in cancer cells.

Pub. Date : 2016 Sep

PMID : 27385486






1 Functional Relationships(s)
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1 Herein, we report that GOF mutant R175H and R273H p53 proteins trigger PKM2 phosphorylation on Tyr 105 through the involvement of mTOR signaling. Tyrosine tumor protein p53 Homo sapiens