Title : MiR-124 suppresses the chemotactic migration of rat mesenchymal stem cells toward HGF by downregulating Wnt/β-catenin signaling.

Pub. Date : 2016 Sep

PMID : 27377850






1 Functional Relationships(s)
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1 Consistently, activation of the Wnt/beta-catenin signaling pathway by LiCl and DeltaN89beta-catenin rescued the inhibitory effect of miR-124 on the chemotactic migration of rMSCs toward HGF, while inhibition of Wnt/beta-catenin signaling by FH535 abrogated the enhanced chemotactic response achieved by the miR-124 inhibitor. Lithium Chloride catenin beta 1 Rattus norvegicus