Title : Transforming growth factor β-related genes in human retinal pigment epithelial cells after tacrolimus treatment.

Pub. Date : 2016 Oct

PMID : 27372923






4 Functional Relationships(s)
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1 Transforming growth factor beta-related genes in human retinal pigment epithelial cells after tacrolimus treatment. Tacrolimus transforming growth factor beta 1 Homo sapiens
2 Therefore, the aim of this study was to investigate the expression profile of TGFbeta isoforms, their receptors, and TGFbeta-related genes in human retinal pigment epithelial cells (RPE) after tacrolimus (FK-506) treatment in the presence or absence of lipopolysaccharide (LPS)-induced inflammation. Tacrolimus transforming growth factor beta 1 Homo sapiens
3 Therefore, the aim of this study was to investigate the expression profile of TGFbeta isoforms, their receptors, and TGFbeta-related genes in human retinal pigment epithelial cells (RPE) after tacrolimus (FK-506) treatment in the presence or absence of lipopolysaccharide (LPS)-induced inflammation. Tacrolimus transforming growth factor beta 1 Homo sapiens
4 RESULTS: Analysis using oligonucleotide microarrays revealed 20 statistically significant differentially expressed TGFbeta-related genes after LPS treatment in relation to control cells, and after tacrolimus and LPS treatment in relation to LPS-treated cells. Tacrolimus transforming growth factor beta 1 Homo sapiens