Title : Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy.

Pub. Date : 2016 Dec

PMID : 27372563






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The anti-hIgE vector, administered either before sensitization or after peanut sensitization and manifestation of the peanut-induced phenotype, blocked IgE-mediated alterations in peanut-induced histamine release, anaphylaxis scores, locomotor activity, and free IgE levels and protected animals from death caused by anaphylaxis. Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 The anti-hIgE vector, administered either before sensitization or after peanut sensitization and manifestation of the peanut-induced phenotype, blocked IgE-mediated alterations in peanut-induced histamine release, anaphylaxis scores, locomotor activity, and free IgE levels and protected animals from death caused by anaphylaxis. Histamine immunoglobulin heavy constant epsilon Homo sapiens
3 The anti-hIgE vector, administered either before sensitization or after peanut sensitization and manifestation of the peanut-induced phenotype, blocked IgE-mediated alterations in peanut-induced histamine release, anaphylaxis scores, locomotor activity, and free IgE levels and protected animals from death caused by anaphylaxis. Histamine immunoglobulin heavy constant epsilon Homo sapiens