Title : Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.

Pub. Date : 2016 Aug 26

PMID : 27365393






1 Functional Relationships(s)
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1 Comparative molecular dynamics indicated that Ser(36) upon phosphorylation will pull the first luminal loop of LTC4S toward the neighboring subunit of the functional homotrimer, thereby forming hydrogen bonds with Arg(104) in the adjacent subunit. Hydrogen leukotriene C4 synthase Homo sapiens