Title : A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors.

Pub. Date : 2016 Nov

PMID : 27353308






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 5-HT1B receptors are inhibitory GPCRs located on the presynaptic terminal of both serotonin and non-serotonin neurons, where they act to inhibit neurotransmitter release. Serotonin 5-hydroxytryptamine (serotonin) receptor 1B Mus musculus
2 5-HT1B receptors are inhibitory GPCRs located on the presynaptic terminal of both serotonin and non-serotonin neurons, where they act to inhibit neurotransmitter release. Serotonin 5-hydroxytryptamine (serotonin) receptor 1B Mus musculus
3 Mice lacking 5-HT1B autoreceptors displayed the expected increases in extracellular serotonin levels in the ventral hippocampus following administration of a selective serotonin reuptake inhibitor. Serotonin 5-hydroxytryptamine (serotonin) receptor 1B Mus musculus