Title : Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.

Pub. Date : 2016 Aug 2

PMID : 27351133






1 Functional Relationships(s)
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1 Here, we report that exposure of MTC cells to a tri-substituted naphthalene diimide (NDI) resulted in a significant antiproliferative activity paralleled by inhibition of RET expression. tri-substituted naphthalene diimide ret proto-oncogene Homo sapiens