Title : New insights into thiocyanate oxidation by human myeloperoxidase.

Pub. Date : 2016 Sep

PMID : 27343172






6 Functional Relationships(s)
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Protein Name
Organism
1 At low thiocyanate concentration and in the presence of hydrogen peroxide the observed reaction sequence is Compound I ferric MPO Compound II MPO-cyanide complex, whereas at high thiocyanate concentrations and in the absence of H2O2 the only observed transition is Compound I ferric MPO. Cyanides myeloperoxidase Homo sapiens
2 At low thiocyanate concentration and in the presence of hydrogen peroxide the observed reaction sequence is Compound I ferric MPO Compound II MPO-cyanide complex, whereas at high thiocyanate concentrations and in the absence of H2O2 the only observed transition is Compound I ferric MPO. Cyanides myeloperoxidase Homo sapiens
3 At low thiocyanate concentration and in the presence of hydrogen peroxide the observed reaction sequence is Compound I ferric MPO Compound II MPO-cyanide complex, whereas at high thiocyanate concentrations and in the absence of H2O2 the only observed transition is Compound I ferric MPO. Cyanides myeloperoxidase Homo sapiens
4 The reaction of ferric MPO with hypothiocyanite directly forms the MPO-cyanide complex, whereas a transient product derived from the reaction between hypothiocyanite and hydrogen peroxide is demonstrated to mediate the conversion of ferric MPO to Compound II. Cyanides myeloperoxidase Homo sapiens
5 The reaction of ferric MPO with hypothiocyanite directly forms the MPO-cyanide complex, whereas a transient product derived from the reaction between hypothiocyanite and hydrogen peroxide is demonstrated to mediate the conversion of ferric MPO to Compound II. Cyanides myeloperoxidase Homo sapiens
6 The reaction of ferric MPO with hypothiocyanite directly forms the MPO-cyanide complex, whereas a transient product derived from the reaction between hypothiocyanite and hydrogen peroxide is demonstrated to mediate the conversion of ferric MPO to Compound II. Cyanides myeloperoxidase Homo sapiens