Title : Development of a prediction system for anti-tuberculosis drug-induced liver injury in Japanese patients.

Pub. Date : 2016

PMID : 27340556






3 Functional Relationships(s)
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1 Previous reports in several populations have consistently demonstrated an association between polymorphisms in the N-acetyltransferase 2 (NAT2) gene, which is responsible for INH hepatic metabolism, and a risk of DILI in TB patients. Terbium N-acetyltransferase 2 Homo sapiens
2 Previous reports in several populations have consistently demonstrated an association between polymorphisms in the N-acetyltransferase 2 (NAT2) gene, which is responsible for INH hepatic metabolism, and a risk of DILI in TB patients. Terbium N-acetyltransferase 2 Homo sapiens
3 The findings demonstrated that slow NAT2 acetylator status is a significant predictor of the risk of DILI by anti-TB agents, and a personalized anti-TB treatment approach may aid in making treatment decisions and reducing the incidence of DILI. Terbium N-acetyltransferase 2 Homo sapiens