Title : Homocysteine induces PUMA-mediated mitochondrial apoptosis in SH-SY5Y cells.

Pub. Date : 2016 Nov

PMID : 27339788






1 Functional Relationships(s)
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1 Homocysteine significantly increased mRNA levels of CHOP and p53, resulting in the upregulation of their downstream target gene, p53 up-regulated modulator of apoptosis (PUMA). Homocysteine DNA damage inducible transcript 3 Homo sapiens