Pub. Date : 2017 Jul
PMID : 27324791
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PQ selectively induced metabolomic alterations and adenosine monophosphate-activated protein kinase (AMPK) activation in the midbrain and striatum of mice chronically treated with PQ. | Paraquat | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
2 | PQ selectively induced metabolomic alterations and adenosine monophosphate-activated protein kinase (AMPK) activation in the midbrain and striatum of mice chronically treated with PQ. | Paraquat | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
3 | Inhibition of AMPK signaling led to metabolic dysfunction and an enhanced sensitivity of dopaminergic cells to PQ. | Paraquat | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
4 | In addition, activation of AMPK by PQ was prevented by inhibition of the inducible nitric oxide syntase (iNOS) with 1400W, but PQ had no effect on iNOS levels. | Paraquat | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |