Title : Advanced glycation end products inhibit testosterone secretion by rat Leydig cells by inducing oxidative stress and endoplasmic reticulum stress.

Pub. Date : 2016 Aug

PMID : 27315604






2 Functional Relationships(s)
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1 Testosterone production induced by human chorionic gonadotropin (hCG) was determined by ELISA. Testosterone chorionic gonadotropin subunit beta 5 Homo sapiens
2 We found that the AGEs markedly suppressed testosterone production by rat Leydig cells which was induced by hCG in a concentration-dependent manner compared with the control (P<0.01). Testosterone chorionic gonadotropin subunit beta 5 Homo sapiens