Pub. Date : 2016 Dec 1
PMID : 27307593
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EXPERIMENTAL DESIGN AND RESULTS: Buparlisib inhibited AKT activity, decreased proliferation, and induced apoptosis in metastatic melanoma cell lines and short-term brain melanoma cells, irrespective of their BRAF and NRAS mutation status. | NVP-BKM120 | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In addition, buparlisib inhibited hyperactivated AKT and induced apoptosis in melanoma cells that were stimulated with astrocyte-conditioned medium. | NVP-BKM120 | AKT serine/threonine kinase 1 | Homo sapiens |