Title : Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+.

Pub. Date : 1989 Mar 15

PMID : 2730577






2 Functional Relationships(s)
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1 Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Fura-2 coagulation factor II, thrombin Homo sapiens
2 Previous studies of the early kinetics of rises in cytosolic free [Ca2+] in fura-2-loaded human platelets suggested that: (1) Ca2+ entry slightly preceded internal discharge with thrombin and other agonists known to promote inositol lipid hydrolysis; (2) with ADP, Ca2+ entry occurred without measurable delay and clearly preceded internal Ca2+ discharge. Fura-2 coagulation factor II, thrombin Homo sapiens