Title : Suppression of Spleen Tyrosine Kinase (Syk) by Histone Deacetylation Promotes, Whereas BAY61-3606, a Synthetic Syk Inhibitor Abrogates Colonocyte Apoptosis by ERK Activation.

Pub. Date : 2017 Jan

PMID : 27293079






2 Functional Relationships(s)
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Protein Name
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1 Instead, BAY completely abolishes butyrate-induced differentiation and apoptosis in a Syk- and ERK1/2-dependent manner. Butyrates mitogen-activated protein kinase 3 Homo sapiens
2 While butyrate dephosphorylates ERK1/2 in HT-29 cells, BAY re-phosphorylates it, leading to its activation. Butyrates mitogen-activated protein kinase 3 Homo sapiens