Pub. Date : 2016 Sep
PMID : 27284701
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | BACKGROUND: Methadone is a substrate of the permeability glycoprotein (P-gp) efflux transporter, which is encoded by the ABCB1 (MDR1) gene. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | BACKGROUND: Methadone is a substrate of the permeability glycoprotein (P-gp) efflux transporter, which is encoded by the ABCB1 (MDR1) gene. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | Genetic variations in ABCB1 gene may be responsible for the variability in observed methadone concentrations. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | OBJECTIVE: This study investigated the associations of ABCB1 polymorphisms and serum methadone concentration over the 24-hour dosing interval in opioid-dependent patients on methadone maintenance therapy (MMT). | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 7 | OBJECTIVE: This study investigated the associations of ABCB1 polymorphisms and serum methadone concentration over the 24-hour dosing interval in opioid-dependent patients on methadone maintenance therapy (MMT). | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 8 | CONCLUSION: There was an association between the CGC/TTT diplotype of ABCB1 polymorphisms and serum methadone concentration over the 24-hour dosing interval among patients on MMT. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 9 | Genotyping of ABCB1 among opioid-dependent patients on MMT may help individualize and optimize methadone substitution treatment. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |