Pub. Date : 2016
PMID : 27280849
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Although the molecular mechanism by which nelfinavir exerts antitumor activity is still unknown, its effects have been related to Akt inhibition. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Nelfinavir treated tumor cells also displayed a downregulation of the Akt pathway due to disruption of the Akt-HSP90 complex, and subsequent degradation of Akt. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Nelfinavir treated tumor cells also displayed a downregulation of the Akt pathway due to disruption of the Akt-HSP90 complex, and subsequent degradation of Akt. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Nelfinavir treated tumor cells also displayed a downregulation of the Akt pathway due to disruption of the Akt-HSP90 complex, and subsequent degradation of Akt. | Nelfinavir | AKT serine/threonine kinase 1 | Homo sapiens |