Pub. Date : 2016 Jun 6
PMID : 27267902
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Long non-coding RNA ATB promotes glioma malignancy by negatively regulating miR-200a. | 4-anisyltetrazolium blue | microRNA 200a | Homo sapiens |
| 2 | In addition, ATB was confirmed to target miR-200a, and miR-200a inhibition reversed the malignant characteristics of ATB knockdown on glioma cells. | 4-anisyltetrazolium blue | microRNA 200a | Homo sapiens |
| 3 | In addition, ATB was confirmed to target miR-200a, and miR-200a inhibition reversed the malignant characteristics of ATB knockdown on glioma cells. | 4-anisyltetrazolium blue | microRNA 200a | Homo sapiens |
| 4 | In particular, ATB may act as a ceRNA, effectively becoming a sink for miR-200a, thereby modulating the derepression of TGF-beta2. | 4-anisyltetrazolium blue | microRNA 200a | Homo sapiens |
| 5 | CONCLUSIONS: Our findings suggest that ATB plays an oncogenic role of glioma cells by inhibiting miR-200a and facilitating TGF-beta2 in glioma, thereby may represent a potential therapeutic target for the treatment of human glioma. | 4-anisyltetrazolium blue | microRNA 200a | Homo sapiens |