Title : Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport.

Pub. Date : 2016 Jul 15

PMID : 27262425






3 Functional Relationships(s)
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1 Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. Quinidine ATP binding cassette subfamily B member 1 Homo sapiens
2 In the present study, we evaluated the inhibition of P-gp-mediated quinidine transport by two series of DBHs and performed a classical QSAR analysis and docking simulation in order to investigate the mechanisms underlying P-gp substrate/inhibitor recognition. Quinidine ATP binding cassette subfamily B member 1 Homo sapiens
3 In the present study, we evaluated the inhibition of P-gp-mediated quinidine transport by two series of DBHs and performed a classical QSAR analysis and docking simulation in order to investigate the mechanisms underlying P-gp substrate/inhibitor recognition. Quinidine ATP binding cassette subfamily B member 1 Homo sapiens