Title : Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy.

Pub. Date : 2016 Jun 15

PMID : 27260406






1 Functional Relationships(s)
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1 In addition, steroid production in retina is also increased which, in conjunction with high circulating levels, impairs estrogen receptor expression and mitochondrial respiratory complex IV activity, promoting RGC apoptosis in females. Steroids estrogen receptor 1 Homo sapiens