Pub. Date : 2017 Jan
PMID : 27256568
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we investigated whether oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages, leading to the secretion of IL-1beta. | Phosphatidylcholines | interleukin 1 beta | Mus musculus |
| 2 | Our results demonstrate that endogenously produced oxidized phosphatidylcholines such as POVPC induce the activation of NLRP3 inflammasome, leading to the production of IL-1beta in macrophages. | Phosphatidylcholines | interleukin 1 beta | Mus musculus |