Pub. Date : 2016 Jun 2
PMID : 27253067
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body beta-hydroxybutyrate. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Mus musculus |
| 2 | Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body beta-hydroxybutyrate. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Mus musculus |
| 3 | The metabolite beta-hydroxybutyrate, which increases after prolonged exercise, induces the activities of Bdnf promoters, particularly promoter I, which is activity-dependent. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Mus musculus |
| 4 | We have discovered that the action of beta-hydroxybutyrate is specifically upon HDAC2 and HDAC3, which act upon selective Bdnf promoters. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Mus musculus |
| 5 | Moreover, the effects upon hippocampal Bdnf expression were observed after direct ventricular application of beta-hydroxybutyrate. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Mus musculus |