Title : Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy.

Pub. Date : 2016 Jun 1

PMID : 27251615






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The receptor is activated by the release of ATP from intracellular sources that occurs during neurodegeneration, leading to microglial activation and inflammasome-mediated interleukin 1beta release that contributes to neuroinflammation. Adenosine Triphosphate interleukin 1 beta Mus musculus