Title : Bis(hinokitiolato)zinc complex ([Zn(hkt)2]) activates Akt/protein kinase B independent of insulin signal transduction.

Pub. Date : 2016 Jul

PMID : 27251140






2 Functional Relationships(s)
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1 Since many Zn complexes have been developed to enhance the insulin-like activity and increase the exposure and residence of Zn in the animal body, these complexes are recognized as one of the new candidates with action mechanism different from existing anti-diabetic drugs. Zinc insulin Homo sapiens
2 Therefore, we evaluated the activity of Zn complexes, especially related to the phosphorylation of insulin signaling pathway components. Zinc insulin Homo sapiens