Title : Relationship between the plasma fentanyl and serum 4β-hydroxycholesterol based on CYP3A5 genotype and gender in patients with cancer pain.

Pub. Date : 2016 Jun

PMID : 27236640






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Relationship between the plasma fentanyl and serum 4beta-hydroxycholesterol based on CYP3A5 genotype and gender in patients with cancer pain. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 This study aimed to evaluate the relationship between the concentrations of plasma fentanyl and serum 4beta-hydroxycholesterol based on CYP3A5 genotype and gender in cancer patients. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens
3 The serum 4beta-hydroxycholesterol concentration and its ratio to total cholesterol were significantly lower in the CYP3A5*3/*3 group than in the *1 allele carrier group. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens
4 In conclusion, CYP3A5*3 and gender affected the plasma fentanyl and serum 4beta-hydroxycholesterol concentrations in cancer patients. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens