Title : Role of oxidative stress in disrupting the function of negative glucocorticoid response element in daily amphetamine-treated rats.

Pub. Date : 2016 Sep

PMID : 27235634






2 Functional Relationships(s)
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1 Pretreatment with GR inhibitor or ROS scavenger modulated mRNA levels in NPY, POMC, SOD and CRH in AMPH-treated rats. Amphetamine proopiomelanocortin Rattus norvegicus
2 We suggest that disruptions of negative GRE (nGRE) on Day 1 and Day 2 are associated with an increase in oxidative stress during the regulation of NPY/POMC-mediated appetite control in AMPH-treated rats. Amphetamine proopiomelanocortin Rattus norvegicus