Title : Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.

Pub. Date : 2016 Jun 23

PMID : 27232526






1 Functional Relationships(s)
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1 Tetrahydroisoquinoline derivatives containing embedded urea functions were identified as selective TRPM8 channel receptor antagonists. 1,2,3,4-tetrahydroisoquinoline transient receptor potential cation channel subfamily M member 8 Homo sapiens