Pub. Date : 2016 Aug
PMID : 27231830
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies. | indolopyrazoline | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been characterized and evaluated as potential anti-Alzheimer agents through in vitro Acetylcholinesterase (AChE) inhibition and radical scavenging activity (antioxidant) studies. | indolopyrazoline | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
3 | The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been characterized and evaluated as potential anti-Alzheimer agents through in vitro Acetylcholinesterase (AChE) inhibition and radical scavenging activity (antioxidant) studies. | indolopyrazoline | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
4 | Finally, molecular docking studies provided prospective evidence to identify key interactions between the active inhibitors and the AChE that furthermore led us to the identification of plausible binding mode of novel indolopyrazoline derivatives. | indolopyrazoline | acetylcholinesterase (Cartwright blood group) | Homo sapiens |