Title : Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies.

Pub. Date : 2016 Aug

PMID : 27231830






4 Functional Relationships(s)
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1 Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies. indolopyrazoline acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been characterized and evaluated as potential anti-Alzheimer agents through in vitro Acetylcholinesterase (AChE) inhibition and radical scavenging activity (antioxidant) studies. indolopyrazoline acetylcholinesterase (Cartwright blood group) Homo sapiens
3 The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been characterized and evaluated as potential anti-Alzheimer agents through in vitro Acetylcholinesterase (AChE) inhibition and radical scavenging activity (antioxidant) studies. indolopyrazoline acetylcholinesterase (Cartwright blood group) Homo sapiens
4 Finally, molecular docking studies provided prospective evidence to identify key interactions between the active inhibitors and the AChE that furthermore led us to the identification of plausible binding mode of novel indolopyrazoline derivatives. indolopyrazoline acetylcholinesterase (Cartwright blood group) Homo sapiens