Title : A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis.

Pub. Date : 2016 Aug 19

PMID : 27229194






4 Functional Relationships(s)
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1 In an earlier study, a number of selective COX-2 inhibitors/NO donors were developed by conjugating a diarylpyrrole scaffold endowed with selective COX-2 inhibitory properties with various nitrooxyalkyl side chains such as esters, alpha-amino esters, amides, alpha-amino amides, ethers, beta-amino ethers, inverse esters, and amides. Esters prostaglandin-endoperoxide synthase 2 Homo sapiens
2 In an earlier study, a number of selective COX-2 inhibitors/NO donors were developed by conjugating a diarylpyrrole scaffold endowed with selective COX-2 inhibitory properties with various nitrooxyalkyl side chains such as esters, alpha-amino esters, amides, alpha-amino amides, ethers, beta-amino ethers, inverse esters, and amides. Esters prostaglandin-endoperoxide synthase 2 Homo sapiens
3 In an earlier study, a number of selective COX-2 inhibitors/NO donors were developed by conjugating a diarylpyrrole scaffold endowed with selective COX-2 inhibitory properties with various nitrooxyalkyl side chains such as esters, alpha-amino esters, amides, alpha-amino amides, ethers, beta-amino ethers, inverse esters, and amides. Esters prostaglandin-endoperoxide synthase 2 Homo sapiens
4 In an earlier study, a number of selective COX-2 inhibitors/NO donors were developed by conjugating a diarylpyrrole scaffold endowed with selective COX-2 inhibitory properties with various nitrooxyalkyl side chains such as esters, alpha-amino esters, amides, alpha-amino amides, ethers, beta-amino ethers, inverse esters, and amides. Esters prostaglandin-endoperoxide synthase 2 Homo sapiens