Title : Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins.

Pub. Date : 2016 Jul 8

PMID : 27226597






1 Functional Relationships(s)
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1 We used the genetic code expansion concept to produce natively folded, site-specific, and lysine-acetylated Sirt1-3 substrate proteins, namely Ras-related nuclear, p53, PEPCK1, superoxide dismutase, cyclophilin D, and Hsp10, and analyzed the deacetylation reaction. Lysine tumor protein p53 Homo sapiens