Pub. Date : 2016 Jun
PMID : 27208730
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The glucocorticoid receptor (GcR) antagonist, mifepristone (10muM) prevented dexamethasone from inhibiting insulin"s action. | Dexamethasone | insulin | Homo sapiens |
| 2 | Strikingly, this anti-insulin action of dexamethasone was also blocked by two CB1 cannabinoid receptor (CB1R) antagonists, O-2050 (500nM) and SR141716A (500nM), as well as by tetrahydrolipstatin (10muM), an inhibitor of diacylglycerol lipases-the enzymes responsible for the synthesis of the endocannabinoid, 2-arachidonoyl-glycerol (2-AG). | Dexamethasone | insulin | Homo sapiens |