Title : Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta.

Pub. Date : 2016 May 20

PMID : 27207105






2 Functional Relationships(s)
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1 Simvastatin was the most potent inhibitor of sFlt-1 secretion from endothelial cells (IC 50 3.2 muM), trophoblast cells (IC 50 61.4 muM) and placental explants. Simvastatin latexin Homo sapiens
2 Simvastatin was the most potent inhibitor of sFlt-1 secretion from endothelial cells (IC 50 3.2 muM), trophoblast cells (IC 50 61.4 muM) and placental explants. Simvastatin latexin Homo sapiens