Title : Isotetrandrine ameliorates tert-butyl hydroperoxide-induced oxidative stress through upregulation of heme oxygenase-1 expression.

Pub. Date : 2016 Aug

PMID : 27190261






2 Functional Relationships(s)
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1 Isotetrandrine ameliorates tert-butyl hydroperoxide-induced oxidative stress through upregulation of heme oxygenase-1 expression. tert-Butylhydroperoxide heme oxygenase 1 Homo sapiens
2 These results indicated that the 1R, 1"S-isotetrandrine ameliorated tert-butyl hydroperoxide-induced oxidative damage through upregulation of heme oxygenase-1 expression by the dissociation of Nrf2 from Nrf2-Keap1 complex via extracellular signal-regulated protein kinase and c-Jun NH2-terminal kinase activation and Keap1 inactivation. tert-Butylhydroperoxide heme oxygenase 1 Homo sapiens