Title : Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation.

Pub. Date : 2016

PMID : 27182202






1 Functional Relationships(s)
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1 Augmented downregulation of c-Myc protein expression was observed in the combination treatment with ATRA, VD3 and dasatinib compared to treatment with each reagent alone in HL-60 cells. Tretinoin MYC proto-oncogene, bHLH transcription factor Homo sapiens