Title : LRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesias.

Pub. Date : 2016 May 11

PMID : 27169991






2 Functional Relationships(s)
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1 LRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesias. Levodopa leucine rich repeat kinase 2 Homo sapiens
2 Here we show that LRRK2 phosphorylation level at serine 935 correlates with LIDs induction and that inhibition of LRRK2 induces a significant increase in the dyskinetic score in L-DOPA treated parkinsonian animals. Levodopa leucine rich repeat kinase 2 Homo sapiens