Title : Parallel Chemical Protein Synthesis on a Surface Enables the Rapid Analysis of the Phosphoregulation of SH3 Domains.

Pub. Date : 2016 Jun 13

PMID : 27161995






1 Functional Relationships(s)
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1 The analysis suggests that tyrosine phosphorylation of SH3 domains found in Abl kinases act as a switch that can induce both the loss and, unexpectedly, gain of affinity for proline-rich ligands. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens