Title : The shifting landscape of KATP channelopathies and the need for 'sharper' therapeutics.

Pub. Date : 2016 May

PMID : 27161588






1 Functional Relationships(s)
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1 Small-molecule inhibitors (e.g., sulfonylurea drugs) or activators (e.g., diazoxide) acting on SUR1 or SUR2 have been used clinically for decades to manage the inappropriate secretion of insulin in patients with Type 2 diabetes, hyperinsulinism and intractable hypertension. Diazoxide ATP binding cassette subfamily C member 9 Homo sapiens