Title : Tissue-infiltrating plasma cells are an important source of carboxylesterase 2 contributing to the therapeutic efficacy of prodrugs.

Pub. Date : 2016 Aug 1

PMID : 27149931






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Carboxylesterase 2 (CES-2) is instrumental for conversion of ester-containing prodrugs in cancer treatment. Esters carboxylesterase 2 Homo sapiens
2 In summary, the conversion of ester-containing prodrugs by CES-2 is mainly to occur in the periphery, during liver passage and in the colon after enterohepatic recirculation. Esters carboxylesterase 2 Homo sapiens