Title : Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells.

Pub. Date : 2016 Apr 30

PMID : 27137793






2 Functional Relationships(s)
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1 BACKGROUND: Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx), particularly glutathione peroxidase-1 (GPx-1). Glucose superoxide dismutase 1 Homo sapiens
2 RESULTS: After exposure to constant high glucose SOD-1 and GPx-1 increased, while in oscillating glucose SOD-1 increased and GPx-1 did not. Glucose superoxide dismutase 1 Homo sapiens